ccache is a compiler cache. It speeds up recompilation of C/C++ code by caching previous compilations and detecting when the same compilation is being done again. This often results in a significant speedup in common compilations, especially when switching between branches. This page is about using ccache on Mac with clang and the Ninja build system.
To install ccache with Homebrew, run brew install ccache. With MacPorts, run port install ccache. You can also download and install yourself, using the instructions in the repository.
Make sure ccache can be found in your $PATH.
You just need to set the cc_wrapper GN variable. You can do so by running gn args out/Default and adding cc_wrapper="env CCACHE_SLOPPINESS=time_macros ccache" to the build arguments.
After setting the cc_wrapper GN variable you can just run ninja as normal:
ninja -C out/Default chrome
ccache -M <max size>. You can see a list of configuration options by calling ccache alone.